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Title   Lyophyllum decastes 의 항암성분의 면도학적 연구 ( 2 ) ( Immunological Studies on the Antitumor Component of Lyophyllum decastes ( 2 ) )
Publicationinfo   1987 Jan; 019(02): 57-63.
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Abstract   Lyophyllan A was isolated as an antitumor component from Lyophyllum decstes. To elucidate mechanisms of its antitumor activity, its effects on immune response were examined. Lyophyllan A restored the suppressed delayed-type hypersensitivity reaction in tumor-bearing mice up to 85.7% of the normal level. Also lyophyllan A enhanced in vivo generation of cytotoxic T-lymphocytes. When effects of lyophyllan A on natural killer cells that are one of the important nonspecific evvector cells were examined, it augmented natural killer activity in the spleen cells of mice. These results showed that lyophyllan A is an immunopotentiator.
저 자   이정옥(Chang Ock Lee),최응칠(Eung Chil Choi),김병각(Byong Kak Kim)